The Institute for Safe Medication Practices recently reported on several mix-ups between two vaccines. The first is DAPTACEL, which is diphtheria and tetanus toxoids and acellular pertussis vaccine adsorbed (DTaP). The second is ADACEL, which is tetanus toxoid, reduced diphtheria toxoid, and acellular pertussis vaccine adsorbed (Tdap). Daptacel is used in infants and children 6 weeks to 6 years old for active immunization. Adacel is used for active booster immunization in persons 11 to 64 years old and it is also the first vaccine approved as a pertussis booster for adults. The component antigens in Adacel and Daptacel are the same, so ISMP says this contributes to making them easy to confuse. In one clinic, 13 adults were mistakenly vaccinated with Daptacel. At another clinic, seven adults received Daptacel instead of Adacel. Fortunately, none of the patients appeared to have experienced any unusual vaccine reactions, despite the fact that the pediatric formulation contains greater amounts of both the detoxified pertussis toxin and the diphtheria toxoid. ISMP says that the similarities of the brand names, generic designations, and vaccine abbreviations also probably contribute to the confusion. In addition, these two vaccines have similar packaging - both are Aventis Pasteur products and they come in stylized, colorful cartons of the same size. ISMP makes several recommendations to help prevent mix-ups between these two products. • Verify the patient's age before ...
Tags: Adacel, Tdap, Daptacel, dtap, Vaccine, Mix-Up, FDA, Patient, Safety
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